Since our last commentary on the Cell Therapy Catapult clinical trials database, they have released an update expanding to include 34 clinical trials currenty operating in the UK.
This post will give more detail on the commercial companies sponsoring UK clinical trials in cell therapy.
Azellon Cell therapeutics is a spin out company from University of Bristol building on the pioneering work from Professor Anthony Hollander. Professor Hollander was also part of the team involved in the first tissue engineered trachea transplant in Claudia Castillo, as the only stem cell scientist. Azellon have a Phase I/II clinical trial approved for treatment of knee meniscal repair using bone marrow derived mesenchymal stem cells (MSCS) infused onto a biological scaffold.
Reneuron are a publicly limited company, who are the foremost stem cell company in the UK. Their PISCES (Pilot Investigation of Stem Cells in Stroke) is the 'world's first clinical trial of a neural stem cell therapy for disabled stroke patients'. While this is just a safety study, promising initial results application has been made for commencement of a phase II study later this year.